Structural transformation of wireframe DNA origami via DNA polymerase assisted gap-filling

Nayan P. Agarwal, Michael Matthies, Bastian Joffroy, Thorsten L. Schmidt
ACS Nano 2018, DOI:10.1021/acsnano.7b08345
In this work, we have explored the possibility to synthesize the complementary sequences to single-stranded gap regions in the DNA origami scaffold cost effectively by a DNA polymerase rather than by a DNA synthesizer.